Durfee Mills is an historic textile mill complex located at 359-479 Pleasant Street in Fall River, Massachusetts, USA. Developed between 1866 and 1904, it was during its period of development the city's largest and architecturally finest mill complex. Along with the adjacent Union Mills, it is occupied by numerous retail businesses and a restaurant, and is known as the Durfee-Union Mills. The complex was listed on the National Register of Historic Places in 1983.